Figure 1.
Dynamics of germ cell cyst breakdown. (a) Representative IF for oocytes with MVH (green) in tissue sections of ovaries at 0–4 d.p.p. Plenty of oocytes remaining within cysts (arrowheads) at 0–1 d.p.p., and quantification of oocytes were surrounded by pre-granulosa cells and formed primordial follicles (arrows) at 3–4 d.p.p. Scale bars: 50 μm. (b) Percent of oocytes in follicles through 0 to 4 d.p.p.; note acceleration of cyst breakdown between 1 and 3 d.p.p., and quantification of oocyte number at 0–4 d.p.p.; note a marked decrease of the oocyte number between 1 and 3 d.p.p. (c) Number of oocytes per section in mouse ovaries of 0 to 4 d.p.p. Results are presented as mean±S.D. All the experiments were repeated at least three times