Table 4.
Correlations between PFC transcript levels in male and female alcohol-naive BXD recombinant inbred strains of mice and alcohol consumption and preference in two-bottle choice (alcohol vs water) drinking models
| Gene | Record ID | Phenotype | PubMed ID | Sex | r | Number of strains | p value |
|---|---|---|---|---|---|---|---|
| Pycr2 | 10156 | Consumption (10% alcohol, g/kg/d) | 8651451 | ♀ | 0.98 | 9 | 4.94−09 |
| 10159 | Consumption (10% alcohol, g/kg/d) | 8651451 | ♂, ♀ | 0.83 | 9 | 0.003 | |
| 10155 | Consumption (10% alcohol, g/kg/d) | 8651451 | ♂ | 0.80 | 9 | 0.007 | |
| 12964 | Consumption (15% alcohol, g/kg/2 h) | 27793543 | ♂, ♀ | 0.69 | 11 | 0.023 | |
| 10581 | Consumption (10% alcohol, g/kg/d) | 7695038 | ♀ | 0.49 | 19 | 0.030 | |
| 10154 | Preference (10% alcohol) | 8651451 | ♀ | 0.95 | 9 | 7.23−06 | |
| 10153 | Preference (10% alcohol) | 8651451 | ♂ | 0.93 | 9 | 5.18−05 | |
| 10158 | Preference (10% alcohol) | 8651451 | ♂, ♀ | 0.85 | 9 | 0.002 | |
| 10583 | Preference (10% alcohol) | 7695038 | ♀ | 0.50 | 19 | 0.027 | |
| C2cd2l | 10582 | Consumption (10% alcohol, g/kg/d) | 7695038 | ♂ | −0.47 | 19 | 0.044 |
| 10475 | Consumption (3% alcohol, g/kg/d) | 7978106 | ♀ | −0.56 | 17 | 0.019 | |
| 10474 | Consumption (3% alcohol, g/kg/d) | 7978106 | ♀ | −0.56 | 17 | 0.017 | |
| 12745 | Consumption (15% alcohol, g/kg/2 h) | 27793543 | ♂, ♀ | −0.65 | 11 | 0.030 | |
| 10155 | Consumption (10% alcohol, g/kg/d) | 8651451 | ♂ | −0.67 | 9 | 0.049 | |
| 10477 | Consumption (10% alcohol, g/kg/d) | 7978106 | ♀ | −0.67 | 17 | 0.004 | |
| 12964 | Consumption (15% alcohol, g/kg/2 h) | 27793543 | ♂, ♀ | −0.71 | 11 | 0.012 | |
| 10159 | Consumption (10% alcohol, g/kg/d) | 8651451 | ♂, ♀ | −0.73 | 9 | 0.022 | |
| 10584 | Preference (10% alcohol) | 7695038 | ♀ | −0.47 | 19 | 0.043 | |
| 10588 | Preference (10% alcohol) | 7695038 | ♂, ♀ | −0.52 | 19 | 0.022 | |
| 10583 | Preference (10% alcohol) | 7695038 | ♀ | −0.55 | 19 | 0.013 | |
| 10153 | Preference (10% alcohol) | 8651451 | ♂ | −0.81 | 9 | 0.005 | |
| Diras2 | 12623 | Consumption (10% alcohol, g/kg/d) | n/a | ♂ | −0.70 | 13 | 0.009 |
Data were obtained from GeneNetwork.org. n/a, Not available.