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. 2017 Mar 8;7:44043. doi: 10.1038/srep44043

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Copyright © 2017, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Experimental design. D-Gal, D-galactosamine; CM, conditioned medium; MCP-1, monocyte chemoattractant protein-1; sSiglec-9, secreted ectodomain of sialic acid-binding Ig-like lectin-9; i.v., intravenous injection; i.p., intraperitoneal injection. (b) Kaplan–Meier survival analysis of SHED-CM, dSHED-CM, and DMEM treatment groups. The log rank test was used to compare the SHED-CM (n = 11) and dSHED-CM (n = 10) groups (P = 0.002), and the SHED-CM and DMEM (n = 10) groups (P = 0.002). ∗∗P < 0.01. (c) Representative images of HE-stained livers. Scale bar: 100 μm. Pre, pre-treatment. (d) Levels of the indicated mRNAs in the livers of CM-treated rats. Results are expressed relative to the level in the sham-operated model. Data represent the mean ± standard error of the mean (SEM) (n = 4 per group); ∗P < 0.05.