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. Author manuscript; available in PMC: 2017 Dec 14.
Published in final edited form as: Cell Host Microbe. 2016 Dec 14;20(6):785–797. doi: 10.1016/j.chom.2016.11.001

Table 1. Top Hit Genes Identified in the shRNA Screen.

The top 10 enriched and disenriched genes with Gene ID, Symbol, Gene Info and log transformed signed P Mann Whitney-value are shown.

#GeneID Symbol GeneInfo Signed log10 P
Top 10
Enriched
Genes
387264 KRTAP5-1 Keratin Associated Protein 5-1 6.516
148170 CDC42EP5 CDC42 Effector Protein (Rho GTPase Binding) 5 4.515
333932 HIST2H3A Histone Cluster 2, H3a 4.51
25827 FBXL2 F-box and Leucine-rich Repeat Protein 2 4.442
25794 FSCN2 Fascin Homolog 2, Actin-bundling Protein, Retinal
(Strongylocentrotus purpuratus)
4.328
147381 CBLN2 Cerebellin 2 Precursor 4.015
2176 FANCC Fanconi anemia, Complementation Group C 3.795
85235 HIST1H2AH Histone Cluster 1, H2ah 3.751
10006 ABI1 Abl-interactor 1 3.749
4179 CD46 CD46 Molecule, Complement Regulatory Protein 3.732
Top 10
Disenriched
Genes
148252 DIRAS1 DIRAS Family, GTP-binding RAS-like 1 −13.326
114902 C1QTNF5 C1q and Tumor Necrosis Factor Related Protein 5 −5.766
1193 CLIC2 Chloride Intracellular Channel 2 −5.666
390667 PTX4 Pentraxin 4, Long −5.466
51005 AMDHD2 Amidohydrolase Domain Containing 2 −5.301
3630 INS Insulin −4.797
220004 PPP1R32 Chromosome 11 Open Reading Frame 66 −4.755
5473 PPBP Pro-platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) −4.69
284353 NKPD1 NTPase, KAP Family P-loop Domain Containing 1 −4.686
50632 CALY Calcyon Neuron-specific Vesicular Protein −4.554