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. 2016 Dec 20;8(4):6179–6192. doi: 10.18632/oncotarget.14049

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Copyright: © 2017 Feng et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Colony formation in soft agar was determined for the four cell lines shown in the presence of the indicated concentration (in nM) of AZD4547, AZD5363 or both. Controls were treated with vehicle only. Data is expressed relative to vehicle only control (100%). Mean +/– standard error of the mean (SEM) is shown. All treatments showed statistically significant decreases from controls. Asterisks indicate statistically significant differences of combo treatment versus the same concentration of AZD5363; *p < .05; **< p <.01, ***p < .001 by t-test.