Fig. 3.
Fibrous sheath formation does not require GAPDS. Sperm ultrastructure was compared by transmission (A, B, E, and F) and scanning (C and D) electron microscopy. The ribs (R) and columns (C) of the fibrous sheath appear similar in cross sections of sperm from WT (A) and Gapds–/– (B) mice. The outer dense fibers (O) and axonemes are also indistinguishable in these flagellar cross sections. Longitudinal sections of sperm from WT (C and E) and Gapds–/– (D and F) mice show some variation in the spacing between the ribs of the fibrous sheath. (Bar: 0.1 μmin A, B, E, and F;1 μmin C and D.)