Table 2.
Correlations (95% confidence interval) between bacterial taxa and BMI, adjusted for birth weight and duration of breastfeeding, in the total cohort (N = 162), in children with minimal antibiotic exposure (0–1 lifetime courses, N = 50), and children with several antibiotic courses (N = 112).
| Taxon | All | p | Minimal AB | p | Several AB | p |
|---|---|---|---|---|---|---|
| Actinobacteria | −0.21 (−0.36 to −0.06) | 0.01 | −0.05 (−0.33 to 0.25) | 0.76 | −0.28 (−0.45 to −0.09) | <0.01 |
| Bifidobacterium | −0.21 (−0.36 to −0.05) | 0.01 | −0.05 (−0.33 to 0.25) | 0.76 | −0.27 (−0.44 to −0.09) | <0.01 |
| Bifidobacterium infantis | −0.19 (−0.34 to −0.04) | 0.02 | −0.05 (−0.33 to 0.25) | 0.76 | −0.23 (−0.4 to −0.04) | 0.02 |
| Bifidobacterium longum | −0.2 (−0.34 to −0.04) | 0.02 | −0.04 (−0.33 to 0.25) | 0.77 | −0.24 (−0.41 to −0.05) | 0.01 |
| Bifidobacterium pseudocatenulatum | −0.16 (−0.31 to 0) | 0.05 | 0.04 (−0.25 to 0.33) | 0.78 | −0.25 (−0.42 to −0.06) | 0.01 |
| Bifidobacterium thermophilum | −0.16 (−0.31 to 0) | 0.05 | 0.06 (−0.23 to 0.34) | 0.69 | −0.24 (−0.41 to −0.05) | 0.01 |
| Bacteroidetes | 0.05 (−0.11 to 0.2) | 0.57 | 0.3 (0.01 to 0.55) | 0.04 | −0.02 (−0.21 to 0.18) | 0.88 |
| Bacteroides | 0.06 (−0.1 to 0.21) | 0.5 | 0.31 (0.02 to 0.55) | 0.04 | 0 (−0.19 to 0.19) | 0.99 |
| Bacteroides ovatus et rel | 0.05 (−0.11 to 0.2) | 0.57 | 0.36 (0.07 to 0.59) | 0.02 | −0.04 (−0.23 to 0.15) | 0.69 |
| Bacteroides vulgatus et rel | 0.07 (−0.09 to 0.22) | 0.41 | 0.34 (0.06 to 0.57) | 0.02 | −0.01 (−0.2 to 0.18) | 0.92 |
| Prevotella tannerae et rel | 0.13 (−0.03 to 0.28) | 0.11 | 0.49 (0.23 to 0.68) | 0 | −0.01 (−0.2 to 0.18) | 0.91 |
| Firmicutes | 0.23 (0.08 to 0.38) | <0.01 | −0.05 (−0.33 to 0.25) | 0.76 | 0.34 (0.16 to 0.5) | <0.01 |
| Clostridia | 0.08 (−0.09 to 0.23) | 0.36 | −0.26 (−0.51 to 0.03) | 0.08 | 0.21 (0.02 to 0.39) | 0.03 |
| Lachnospira pectinoschiza et rel | 0.15 (−0.01 to 0.31) | 0.06 | 0.02 (−0.27 to 0.31) | 0.9 | 0.23 (0.04 to 0.4) | 0.02 |
| Bacilli | 0.25 (0.09 to 0.39) | <0.01 | 0.21 (−0.09 to 0.47) | 0.17 | 0.25 (0.06 to 0.42) | 0.01 |
| Streptococcus | 0.26 (0.11 to 0.4) | <0.01 | 0.07 (−0.22 to 0.35) | 0.64 | 0.31 (0.13 to 0.48) | <0.01 |
| Streptococcus bovis et rel | 0.24 (0.08 to 0.38) | <0.01 | −0.02 (−0.31 to 0.28) | 0.92 | 0.29 (0.1 to 0.46) | <0.01 |
| Streptococcus intermedius et rel | 0.22 (0.06 to 0.36) | 0.01 | 0.23 (−0.06 to 0.49) | 0.12 | 0.21 (0.02 to 0.38) | 0.03 |
| Streptococcus mitis | 0.22 (0.06 to 0.37) | 0.01 | 0.24 (−0.05 to 0.5) | 0.1 | 0.21 (0.02 to 0.38) | 0.03 |
| Streptococcus mitis et rel | 0.26 (0.11 to 0.41) | <0.01 | 0.1 (−0.2 to 0.38) | 0.52 | 0.32 (0.13 to 0.48) | <0.01 |
| Streptococcus mutans | 0.18 (0.02 to 0.33) | 0.03 | 0.18 (−0.11 to 0.45) | 0.22 | 0.18 (−0.01 to 0.36) | 0.06 |
| Streptococcus parasanguinis | 0.21 (0.05 to 0.36) | 0.01 | 0.21 (−0.09 to 0.47) | 0.17 | 0.21 (0.02 to 0.39) | 0.03 |
| Streptococcus pneumoniae | 0.19 (0.03 to 0.34) | 0.02 | 0.07 (−0.22 to 0.36) | 0.63 | 0.22 (0.03 to 0.39) | 0.02 |
| Streptococcus salivarius | 0.24 (0.08 to 0.39) | <0.01 | 0.07 (−0.23 to 0.35) | 0.65 | 0.28 (0.1 to 0.45) | <0.01 |
| Streptococcus sanguis | 0.28 (0.12 to 0.42) | <0.01 | 0.03 (−0.26 to 0.32) | 0.82 | 0.34 (0.16 to 0.5) | <0.01 |