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. 2016 Jul 28;7(39):64447–64470. doi: 10.18632/oncotarget.10901

Table 4. Androgen receptor splice variants.

Variant Protein Regions Activity References
ARV7 (AR3) NTD, DBD Ligand-independent, Nuclear [119–120,122–123, 126]
ARv567es NTD, DBD, Hinge Ligand-independent, Nuclear [121, 126]
ARV12 NTD, DBD, Hinge Ligand-independent, Nuclear [123]
AR1/2/2b (ARV3) NTD, partial DBD Ligand-independent [118–120]
AR1/2/3/2b (ARV4, AR5) NTD, DBD Ligand-independent [118–120]
ARV1 (AR4) NTD, DBD LNCaP: Ligand-independent, PC3: Inactive, Cytoplasmic [119–120, 123,126]
ARV9 NTD, DBD LNCaP: Ligand-independent, PC3: Inactive, Cytoplasmic [123, 126]
ARV13 NTD, DBD, Hinge, partial LBD Inactive [123]
ARV2 NTD, DBD Not determined [119]
ARV5/V6 NTD, DBD Not determined [119]
ARV8/10/11 NTD, DBD Not determined [126]
ARV14 NTD, DBD, Hinge, partial LBD Not determined [123]