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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Biochim Biophys Acta. 2015 Dec 17;1860(3):588–598. doi: 10.1016/j.bbagen.2015.12.012

Figure 3. Deficiency of Syk elevated IFNβ production and leads to the enhancement of STATs phosphorylation.

Figure 3

Wild type and Syk deficiency cells were pretreated with IFNβ neutralizing antibody or isotype control for 2 h and then stimulated with LPS. Cell lysates were prepared at the indicated time points and then analyzed by Western blot. (A) Blots were probed with antibodies to phospho-STATs and GAPDH as a loading control; (B) Densitometric quantification of the ratio of phospho-STATs to total-GAPDH.