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. 2016 Dec 14;6(1):e1257452. doi: 10.1080/2162402X.2016.1257452

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© 2017 The Author(s). Published with license by Taylor & Francis Group, LLC

This is an Open Access article distributed under the terms of the Creative Commons Attribution-Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The moral rights of the named author(s) have been asserted.

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Figure 2. — (A) Flow cytometry data represented as the mean percentage of CD4⁺ T cells, CD8⁺ T cells and B cells among total CD45⁺ cells in breast tumors compared with normal breast tissues or NANT. (B) The same lymphocyte subsets are shown for breast tumors divided into TIL^neg, TIL^int and TIL^hi density groups. (C) CD4⁺/CD8⁺ ratio in breast tumors compared with normal breast tissues or NANT. (D) CD4⁺/CD8⁺ ratio in breast tumors divided into TIL^neg, TIL^int and TIL^hi density groups. (E-G) CD4⁺ T cell, CD8⁺ T cell and CD19⁺ B-cell TIL in normal, NANT or tumor tissues separated into naïve vs. memory cell CD45RA/RO (CD45RA^+/− for T cells and CD27^+/− for B cells). The level of significance is shown as a p value (*p < 0.05, **p < 0.01, ***p < 0.001).