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. Author manuscript; available in PMC: 2017 Apr 1.
Published in final edited form as: Gastroenterology. 2016 Jan 5;150(4):931–943. doi: 10.1053/j.gastro.2015.12.036

Figure 4.

Figure 4

TP53 mutation spectrum in IBD-associated CRC. A. Mutation signature of 19 IBD-associated tumors with TP53 mutations compared to that of all somatic TP53 mutations in human sporadic CRC obtained from the IARC TP53 database (http://p53.iarc.fr/). B. Distribution of TP53 single nucleotide substitutions in IBD-associated CRC. C. Distribution of TP53 single nucleotide substitutions in sporadic CRC obtained from the IARC TP53 database. D. Distribution of TP53 single nucleotide substitutions in sporadic CRC identified by exome sequencing in the TCGA study, obtained from cBioPortal (http://www.cbioportal.org/).