Table 2.
Antimicrobial resistance genes identified against various antimicrobial agents in CR K. pneumoniae.
| Isolate | β-Lactamase | Aminoglycoside | Fluoroquinolones | Fosfomycin | Macrolides | Phenicol | Rifampicin | Sulphonamide | Tetracycline | Trimethoprim |
|---|---|---|---|---|---|---|---|---|---|---|
| CRKP1 | TEM-1A, OXA-232*, OXA-1, SHV-28, CTX-M-15 | aadA2, aacA4, armA | aac(6′)lb-cr, oqxB, oqxA, | fosA | msr(E), mph(E) | catB3 | – | sul1 | tet(D) | dfrA14, dfrA12, dfrA1 |
| CRKP2 | OXA-1, CTX-M-15, OXA-232*, TEM-1B, SHV-28 | aadA2, aacA4, armA | aac(6′)lb-cr, oqxB, oqxA | fosA | msr(E), mph(A), erm(B), mph(E) | catB3 | – | sul1 | tet(D) | dfrA12, dfrA1, dfrA14 |
| CRKP3 | OXA-232* | – | – | – | – | – | – | sul1 | – | – |
| CRKP4 | TEM-1B, CTX-M-15, SHV-12, OXA-232* | aadA2, aacA4 | aac(6′)lb-cr, QnrS1 | fosA | mph(A), erm(B) | catA1 | ARR-2 | sul1 | – | drfA12 |
| CRKP5 | TEM-124, OXA-232*, SHV-12, CTX-M-15 | aadA2, aacA4, rmtF | aac(6′)lb-cr, oqxA | fosA | mph(A), erm(B) | catA1 | ARR-2 | sul1 | – | drfA12 |
| CRKP6 | OXA-1, CTX-M-15, OXA-232*, NDM-1, SHV-28, TEM-1A | aadA2, aacA4, armA, aph(3′)VIa | aac(6′)lb-cr, oqxA, oqxB | fosA | msr(E), mph(A), | catB3 | fosA | sul1 | tet(D) | dfrA14, dfrA12, dfrA1 |
| CRKP7 | TEM-1B, CTX-M-15, SHV-12, OXA-232* | aadA2, aacA4 | aac(6′)lb-cr, oqxA, QnrS1 | fosA | mph(A), erm(B) | catA1 | ARR-2 | sul1 | – | drfA12 |
| CRKP8 | TEM-1B, CTX-M-15, OXA-181*, SHV-11 | strA, rmtF, aacA4 | QnrB66, oqxB, oqxA, aac(6′)lb-cr | fosA | mph(A) | – | ARR-2 | sul2 | – | dfrA12, dfrA14 |
*
Variant of blaOXA−48 like gene.