Table 2.
Top 6 in silico predicted H-2Db and H-2Kb candidate SMA-560-derived neoantigens with the corresponding amino acid sequence. The mutated amino acid is denoted by bold and underlining.
| H-2Db Restriction | |
|---|---|
| Amino acid mutation | Neoantigen sequence |
| mOdc1 Q129L | YAASNGVLM |
| mDock11 G1958V | SVQVNAVPL |
| mPlekhg6 G10C | FGPPNECPL |
| mAtp11b K884M | FFYMNVCFI |
| mNcapd3 V510L | NTVLNPSPL |
| mIfit2 V60I | ATMCNILAYI |
| H-2Kb Restriction | |
| Amino acid mutation | Neoantigen sequence |
| mENSMUSG00000074999 C15F | SSFIYAYI |
| mLama5 G897V | VRFVFNPL |
| mE2f8 K272R | MSQRFVML |
| mAtp11b K884M | VQYFFYMNV |
| mMertk R682P | TFLLYSPL |
| mStt3b G323V | AAVVFALL |