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. 2004 Aug 25;5:13. doi: 10.1186/1471-2199-5-13

Table 5.

Search of MKL-dependent and -independent serum-inducible promoters for SRF binding sites.

A. Exact matches to CArG box
genes in micro-array genes in DBTSS matches frequency p genes with matches frequency p genes w. >1 matches frequency p
Total genes 14824 6875 419 0.061 401 0.058 15 0.002
All Serum-inducible 150 95 17 0.179 0.0001 11 0.116 0.0218 3 0.032 0.0010
MKL-indep, serum-inducible 122 75 14 0.187 0.0002 9 0.120 0.0293 2 0.027 0.0101
MKL-dep, serum-inducible 28 20 3 0.150 0.1193 2 0.100 0.3245 1 0.050 0.0392
B. Matches to CArG box allowing one base mismatch
Total genes 14824 6875 6707 0.98 4230 0.615 1744 0.254
All Serum-inducible 150 95 103 1.08 0.155 63 0.663 0.1958 25 0.263 0.4576
MKL-indep, serum-inducible 122 75 72 0.96 0.839 47 0.627 0.4682 15 0.200 0.8886
MKL-dep, serum-inducible 28 20 31 1.55 0.005 16 0.800 0.0666 10 0.500 0.0155

The promoters from indicated groups were searched for exact matches with the CArG box sequence CC(A/T)6GG (A) or allowing for one base mismatch (B). Frequency indicates the number of matches divided by the number of DBTSS genes in each category. The p values were calculated based on a binomial distribution except for the value for matches in (B) (column 6 from the left) where the numbers were too large and the Poisson distribution of the frequency of matches per base was used.