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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Interv Cardiol Clin. 2017 Jan;6(1):1–12. doi: 10.1016/j.iccl.2016.08.001

Figure 2. Regional architecture of a hemostatic plug.

Figure 2

A) The properties of the core and shell regions of a hemostatic plug are described. B) The core and shell architecture develops as a result of local platelet agonist gradients that are shaped by physical forces within the platelet mass microenvironment.