Figure 3.
N-Myc overexpression deregulated mitochondrial dynamics. (a) The left panel shows logarithmically growing cells that were interrogated by qRT-PCR for the fusion genes. Experiments were performed in quadruplicate with a minimum of four repeats in each experiment. Right panels show westerns blots of WCL from the same cells. Densitometry was used to quantify the expression of the westerns of a minimum of four separate experiments. Data are expressed as relative fold change in expression in SH-N-Myc cells, with the expression in SH=1. Asterisk denotes P>0.05. (b) Fusion genes and their products were measured in the same manner as described above. (c) Western blots of WCL were used to detect Ser637-phopho-Drp1