Figure 4.
Cav1 silencing attenuates AngII-induced VSMC remodeling in vitro. VSMCs were pretreated with adenovirus encoding Cav1 silencing siRNA or control non-silencing siRNA for 48 hours and were stimulated with AngII (100 nmol/L) for 48 hours. Extracellular collagen accumulation, total cell protein and cell volume were evaluated. Means ± SEM (n=4). *p<0.05 compared with basal. †p<0.05 compared with control AngII stimulation.
