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. Author manuscript; available in PMC: 2016 Dec 7.
Published in final edited form as: Cell Rep. 2016 Nov 22;17(9):2195–2209. doi: 10.1016/j.celrep.2016.10.085

Figure 3. Priming protein immunization generates massive GC responses.

Figure 3

Analysis of GC LN cells from three groups of RMs: 1) unimmunized (‘none’); 2) injected with only PLGA(MPL+R848) (‘adjuvant only’); 3) immunized with either BG505 SOSIP.v5.2 + PLGA(MPL+R848) or BG505 SOSIP.v5.2 + Iscomatrix (‘adjuvant + BG505 SOSIP’).

A. GC Tfh cells, as % of CD4+ T cells.

B. GC B cells, as % of CD20+ B cells.

C. Correlation of GC B cell and GC Tfh frequencies in draining LNs after the 1st immunization.

See also Figure S3.