Table 1.
All models compared for the volume-age analyses. Adjusted R2 is reported for the best-fitting model with the lowest Akaike information criterion corrected for sample size (AICC). Region names (e.g., head, HPC) refer to the regional volume.
| Regression model | Adj. R2 | Regression model | Adj. R2 |
|---|---|---|---|
| Subregions | Follow-up: Subfields within the HPC head | ||
| CA1 | |||
| Head | CA1 ~ HPC + sex + age | 0.76 | |
| head ~ HPC + sex + age | -- | CA1 ~ HPC + sex + age2 | -- |
| head ~ HPC + sex + age2 | 0.78 | CA1 ~ HPC + sex × age | -- |
| head ~ HPC + sex × age | -- | CA1 ~ HPC + sex × age2 | -- |
| head ~ HPC + sex × age2 | -- | CA2/3 | |
| CA2/3 ~ HPC + sex + age | 0.41 | ||
| Body | CA2/3 ~ HPC + sex + age2 | -- | |
| body ~ HPC + sex + age | -- | CA2/3 ~ HPC + sex × age | -- |
| body ~ HPC + sex + age2 | 0.55 | CA2/3 ~ HPC + sex × age2 | -- |
| body ~ HPC + sex × age | -- | DG | |
| body ~ HPC + sex × age2 | -- | DG ~ HPC + sex + age | 0.49 |
| DG ~ HPC + sex + age2 | -- | ||
| Tail | DG ~ HPC + sex × age | -- | |
| tail ~ HPC + sex + age | 0.53 | DG ~ HPC + sex × age2 | -- |
| tail ~ HPC + sex + age2 | -- | SUB | |
| tail ~ HPC + sex × age | -- | SUB ~ HPC + sex + age | -- |
| tail ~ HPC + sex × age2 | -- | SUB ~ HPC + sex + age2 | -- |
| SUB ~ HPC + sex × age | -- | ||
| SUB ~ HPC + sex × age2 | 0.48 | ||
|
| |||
| Follow-up: Subfields within the HPC body | |||
| CA1 | DG | ||
| CA1 ~ HPC + sex + age | -- | DG ~ HPC + sex + age | 0.45 |
| CA1 ~ HPC + sex + age2 | 0.41 | DG ~ HPC + sex + age2 | -- |
| CA1 ~ HPC + sex × age | -- | DG ~ HPC + sex × age | -- |
| CA1 ~ HPC + sex × age2 | -- | DG ~ HPC + sex × age2 | -- |
| CA2/3 | SUB | ||
| CA2/3 ~ HPC + sex + age | 0.31 | SUB ~ HPC + sex + age | 0.45 |
| CA2/3 ~ HPC + sex + age2 | -- | SUB ~ HPC + sex + age2 | -- |
| CA2/3 ~ HPC + sex × age | -- | SUB ~ HPC + sex × age | -- |
| CA2/3 ~ HPC + sex × age2 | -- | SUB ~ HPC + sex × age2 | -- |