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. Author manuscript; available in PMC: 2016 Nov 16.
Published in final edited form as: Cell Rep. 2016 Sep 27;17(1):1–10. doi: 10.1016/j.celrep.2016.08.088

Fig. 1. Platelet and reticulocyte ribosome profiling show abundant 3´UTR RPFs.

Fig. 1

A. Scatter plots of RPF counts per mRNA coding sequence for replicates from a single healthy human donor of primary platelets. Known platelet proteins are highlighted in blue. PTPRC (CD45) is a white blood cell marker (green). B. Replicates of RPF counts from CD71+ primary human reticulocytes. C. Ribosome profile of the HMGB1 mRNA in platelets (upper panel) and Meg01 cells (lower panel). D. Ribosome profile of the EEF2 mRNA from in vitro platelet-like particles (PLPs) (upper panel) and precursor Meg01 cells (lower panel). E. Accumulation of 3´UTR RPFs during erythroid-like differentiation. F and G. Cumulative histograms of relative 3´UTR occupancy for (F) primary human platelets, and cell culture models, and (G) primary reticulocytes and cell culture models.