TABLE 2 .
Genes most frequently downregulated following RSV infectiona
| Weighted score | Gene(s) |
|---|---|
| 9 | CLC |
| 6 | NDUFS1, PFDN5 |
| 5 | RTN1, CAT, FCER1A, TSPAN8, ALOX15, GPR56, KLRB1 |
| 4 | XRCC5, LMNA, UBD, CCT3, HSPA8, GARS |
a
Genes were collated from multiple studies of RSV. A cutoff of a 2-fold decrease in expression was used when available. Genes were weighted as follows on the basis of the studies from which they were collated: human genetic studies, 4; human in vivo microarray studies, 3; human in vitro microarray studies, 2; mouse studies, 1. After weighting, genes were analyzed for multiple hits by a custom Perl script.