Figure 2.
The first three rows of circle plots show the functional networks that significantly differ between the methylphenidate and control groups. The Methylphenidate > Control networks (the methylphenidate networks) are shown in red and the Control > Methylphenidate networks (the unmedicated networks) are shown in blue. Networks were defined separately using task and rest matrices with a range of thresholds at the edge-selection step. Edges in both the high-attention and methylphenidate networks and in both the low-attention and unmedicated networks are shown in bold. The high-attention and low-attention networks, defined to predict performance on an attention task in an independent group of participants, are visualized in the fourth row of circle plots. Nodes are grouped by macroscale region, including the prefrontal cortex, motor cortex, insula, parietal cortex, temporal cortex, occipital cortex, limbic lobe (including the cingulate cortex, amygdala, and hippocampus), cerebellum, subcortex (thalamus and striatum), and brainstem. The right half of the circle represents the right hemisphere of the brain.