Fig. 2.
Reduction of the HGP present in IBD patients. (A) Comparison of percentage of healthy individuals (H) (n = 62) versus IBD-diseased individuals (CD and UC) (n = 102) that harbor each of the 23 core HGPs identified in this study. (B) Percentage of core, common, and unique bacteriophages (unique and low-overlap bacteriophages were pooled) present in all healthy and IBD individuals. Median is shown with a horizontal black bar. The number of core and common bacteriophages that IBD individuals harbor is significantly lower compared with healthy individuals. Significance was calculated using a Sidak’s multiple-comparison test with a 95% confidence interval.