Figure 5.

MiR-196b significantly reduces tumor growth in nude mice. (A) Forced expression of miR-196b in H358 and H1975 suppresses tumor growth rates. (B) Hematoxylin and eosin staining of tumors revealed that the controls had a higher mitotic index (arrows) and more single cell necrosis (arrowheads). Error bars indicate the mean ± SEM, ***P <0.001.