TABLE 3.
Mutational changes of SNPs and DIPs in TDA-exposed lineages and clones of V. anguillarum
| Gene name | Gene product | Mutation type | Amino acid position | Amino acid change | No. of affected clones |
|
|---|---|---|---|---|---|---|
| Control | Exposed | |||||
| fliM | Flagellar motor switch protein | SNP | 48 | Gly to Arg | 8 | 0 |
| fliM | Flagellar motor switch protein | SNP | 54 | Glu to Asp | 0 | 10 |
| fliM | Flagellar motor switch protein | SNP | 230 | Asp to Glu | 4 | 18 |
| —a | Hypothetical protein | DIP | Frameshift | 12 | 27 | |
| comM | Mg chelatase activity | SNP | 1 | Leu to Met | 6 | 20 |
| comM | Mg chelatase activity | DIP | 2 | Pro to frameshift | 6 | 20 |
| comM | Mg chelatase activity | DIP | 306 | Val to frameshift | 6 | 20 |
| kinE | Two-component sensor histidine kinase | SNP | 66 | Ile to Val | 8 | 2 |
| — | Hypothetical protein | SNP | 3 | 15 | ||
| dmlR | HTH-type transcriptional regulator | SNP | 228 | Lys to Arg | 0 | 4 |
| yadH | Transport permease protein | SNP | 157 | Gly to Val | 0 | 6 |
| 90-11-286_01842 | 2-Oxoglutarate/Fe(II)-dependent oxygenase | SNP | 32 | Ala to Glu | 0 | 4 |
| ompD | Outer membrane porin protein | SNP | 272 | Leu to Val | 0 | 4 |
| ftsI | Cell division protein | DIP | 4 | Asn to frameshift | 2 | 0 |
| — | Hypothetical protein | SNP | 0 | 2 | ||
a
—, hypothetical protein.