Figure 2.
Distribution of V-family genes in the expressed IgM+ (a,b), IgG+ (c,d), IgK+ (e,f), and IgL+ (g,h) BCR repertoires of healthy human subjects (a,c,e,g) and untreated macaques (b,d,f,h). Productively rearranged sequences amplified from the expressed BCR repertoires for each human subject (n=5) or animal (n=5) were grouped into sequence clusters and are represented by horizontal bars. V-family assignments are color-coded (color assignments are described below the graphs) and scaled according to the proportion present in each data set.