Table 2.
Relationship of cerebral vessel disease with AD dementia*
| Predictor | Odds Ratio (95% confidence interval) | p value |
|---|---|---|
| AD pathology | 4.40 (3.45–5.61) | <0.0001 |
| Gross infarcts | 1.63 (1.21–2.20) | <0.0014 |
| Microinfarcts | 1.31 (0.96–1.78) | 0.084 |
| Atherosclerosis | 1.33 (1.11–1.58) | 0.0020 |
| Arteriolosclerosis | 1.20 (1.04–1.40) | 0.016 |
See text for description of outcome of AD dementia; single logistic regression model, adjusted for age-at-death, sex, education, and Lewy body pathology; model C-statistic is 0.79 (see reference #39)