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. 2016 Jul 22;6:30311. doi: 10.1038/srep30311

Figure 4. Top IPA-based network involved in chemotaxis and canonical pathway analyses in TLR4-primed hMSCs.

Figure 4

(A) Ingenuity® Bioinformatics pathway analysis of gene networks displaying interactions between genes related to antimicrobial response, inflammatory response, cell-to-cell signaling and interaction, cellular movement, and immune cell trafficking that were differentially expressed in TLR4-primed hMSCs. (B) The most highly represented molecular and cellular functions for differentially expressed genes in TLR4-primed hMSCs. (C) The chemotaxis molecules were highly connected, namely, NF-κB complex and PI3K complex, was assessed using the IPA molecule activity predictor.