Table 2.
Physiological parameters
| Parameter | Treatment | 15 min prior to FPI | 15 min post-FPI |
|---|---|---|---|
| MABP, mmHg | Sham + vehicle | 118.1 ± 6.1 | 117.4 ± 3.8 |
| Sham + A33 | 130.6 ± 4.1 | 129.2 ± 2.7 | |
| TBI + vehicle | 123.2 ± 2.7 | 114.9 ± 4.2 | |
| TBI + A33 | 118.4 ± 3.5 | 111.1 ± 4.1 | |
| Blood pO2 | Sham + vehicle | 120.2 ± 5.6 | 122.6 ± 4.4 |
| Sham + A33 | 158.0 ± 7.0 | 153.8 ± 9.2 | |
| TBI + vehicle | 155.5 ± 8.9 | 142.4 ± 7.0 | |
| TBI + A33 | 153.4 ± 5.7 | 144.2 ± 6.3 | |
| Blood pCO2 | Sham + vehicle | 39.7 ± 0.7 | 38.7 ± 1.0 |
| Sham + A33 | 39.1 ± 1.4 | 38.9 ± 1.1 | |
| TBI + vehicle | 38.7 ± 0.7 | 37.0 ± 0.6 | |
| TBI + A33 | 39.4 ± 0.7 | 36.8 ± 0.6 | |
| Blood pH | Sham + vehicle | 7.43 ± 0.01 | 7.44 ± 0.01 |
| Sham + A33 | 7.46 ± 0.01 | 7.47 ± 0.01 | |
| TBI + vehicle | 7.45 ± 0.01 | 7.47 ± 0.01 | |
| TBI + A33 | 7.44 ± 0.01 | 7.46 ± 0.01 | |
| Head temperature, °C | Sham + vehicle | 36.7 ± 0.0 | 36.7 ± 0.1 |
| Sham + A33 | 36.7 ± 0.1 | 36.7 ± 0.1 | |
| TBI + vehicle | 36.7 ± 0.0 | 36.7 ± 0.0 | |
| TBI + A33 | 36.6 ± 0.0 | 36.7 ± 0.0 | |
| Body temperature, °C | Sham + vehicle | 37.0 ± 0.0 | 37.0 ± 0.0 |
| Sham + A33 | 37.1 ± 0.2 | 37.0 ± 0.1 | |
| TBI + vehicle | 37.0 ± 0.1 | 37.0 ± 0.1 | |
| TBI + A33 | 37.1 ± 0.1 | 36.9 ± 0.1 |
MABP, mean arterial blood pressure; pO2, partial arterial oxygen pressure; pCO2, partial arterial carbon dioxide pressure.