Figure 2. Annotating Translated Sequences with Ribosome Profiling Data.
(A) Detecting translated sequences from elongating ribosome footprint profiling on model transcripts. Differences in footprint density and triplet periodicity indicate translated regions. Truncated protein products cause subtle changes in ribosome density.
(B) Initiation profiling highlights alternative initiation sites clearly.
(C) Alternate translation products can be identified relative to the annotated ORF on a transcript.
