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. Author manuscript; available in PMC: 2016 Nov 11.
Published in final edited form as: Nature. 2016 May 11;533(7604):539–542. doi: 10.1038/nature17671

Extended Data Figure 5. Q-Q plots for the 74 lead EduYears SNPs (or LD proxies) in published GWAS of other phenotypes.

Extended Data Figure 5

SNPs with concordant effects on both phenotypes are pink, and SNPs with discordant effects are blue. SNPs outside the gray area pass Bonferroni-corrected significance thresholds that correct for the total number of SNPs we tested (P < 0.05/74 = 6.8×10-4) and are labeled with their rs numbers. Observed and expected P-values are on a –log10 scale. For the sign concordance test: * P < 0.05, ** P < 0.01, and *** P < 0.001.