Figure 6.
Epigenetic characteristics surrounding boundary regions. From the ChIP-seq data of five epigenetic marks in mouse ESC and cortex cells, we identified peaks (P-value < 0.05) using MACS14 (28). The CTCF and promoter marks (Polymerase II and H3K4me3) are enriched near TD boundaries for both cell types. For the enhancer marks H3K4me1 and H3K27ac, the enrichment patterns near boundaries are slightly depleted in both cell types.
