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. Author manuscript; available in PMC: 2017 Apr 12.
Published in final edited form as: Cell Metab. 2016 Feb 22;23(4):591–601. doi: 10.1016/j.cmet.2016.02.005

Figure 1. Effect of 5% weight loss on subcutaneous adipose tissue gene expression of inflammatory markers.

Figure 1

Subcutaneous abdominal adipose tissue expression of genes involved in inflammation was determined by real-time PCR before (black bars) and after (white bars) 5% weight loss (n = 19) or weight maintenance (n = 12). The effect of time (before vs. after) and differences between groups (weight maintenance vs. weight loss) were evaluated by using repeated measures analysis of variance. Significant time-by-group interactions were followed by appropriate within-and between-group post-hoc tests. Non-normally distributed variables were log transformed for analysis and back transformed for presentation. Data are means ± SEM. No effects of weight loss were detected. †P<0.05 vs. weight maintenance group before and after the intervention. Abbreviations: TNF, tumor necrosis factor; IL6, interleukin 6; MCP1, monocyte chemoattractant protein 1; RANTES, regulated on activation normal T cell expressed and secreted; CD68, cluster of differentiation 68; EMR1, EGF-like module-containing mucin-like hormone receptor-like 1.