Table 7.
Classification of malformations found on magnetic resonance imaging of brain
| Patient No | Month of pregnancy with rash | Classification of malformations of cortical development | Grade of decrease in brain volume* |
|---|---|---|---|
| 1 | Second† | Focal left frontal cortical polymicrogyria | I |
| 2 | Second† | Right frontal and perisylvian polymicrogyria | II |
| 3 | Second† | Right hemimegaloencephaly and polymicrogyria; left pachygyria | III |
| 4 | Second | Bilateral pachygyria predominant in frontal and temporal lobes | II |
| 5 | Third | Bilateral superior frontal gyri pachygyria | III |
| 6 | Third | Bilateral lissencephaly | III |
| 7 | Fourth | Bilateral frontal and perisylvian polymicrogyria | I |
| 8 | Sixth | Bilateral frontal and perisylvian polymicrogyria | II |
*Classification of graduation of brain volume according to visual inspection: I=mild; II=moderate; III=severe.
†All three patients with asymmetrical cortical malformations were presumably infected in second month of pregnancy, which corresponds to period of mother’s rash.