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Spontaneous transmission is not detectably altered in CYP46A1 KO slices. A and B: representative traces of sEPSCs and sIPSCs recorded from WT and KO neurons. C: frequency of sEPSC, sIPSC, and E/I ratio were compared between WT and KO neurons (N = 10 WT cells and 9 KO cells; P > 0.1).