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. Author manuscript; available in PMC: 2017 Feb 17.
Published in final edited form as: Neuron. 2016 Feb 4;89(4):857–866. doi: 10.1016/j.neuron.2016.01.011

Fig 3. Unilateral inhibition of hippocampal-prefrontal input disrupts single unit representations of arm type in the mPFC.

Fig 3

(A) Avoidance behavior during unilateral inhibition of vHPC-mPFC input. (B) Change in theta phase-locking strength in significantly phase-locked units during unilateral inhibition (Arch n=16, p<0.01; eYFP n=11, p=0.4258; Wilcoxon one- sample test). (C) Firing rate map as a function of light for an example mPFC single unit. Top, light off; Bottom, light on. EPM score (see text) at bottom right. (D) EPM score during light on vs light off epochs, for all mPFC single units from Arch mice. Right, mean EPM score as a function of light for units from Arch mice (n=82, p=4.1e-07, Wilcoxon sign rank). (E) Mean EPM score as a function of light for units characterized by significant phase-locking to vHPC theta (left) or by preferred arm type (right). **p<0.01, ***p<0.001; Wilcoxon sign rank paired test.