Skip to main content
. Author manuscript; available in PMC: 2016 Jan 30.
Published in final edited form as: N Engl J Med. 2015 Jul 14;373(5):415–427. doi: 10.1056/NEJMoa1500245

Table 2.

Estimated Annual Incidence Rates of Hospitalization for Community-Acquired Pneumonia, According to Year of Study, Study Site, Age Group, and Pathogen Detected.*

Variable Incidence of Pneumonia-Related
Hospitalization (95% CI)
no. of cases per 10,000 adults per yr

Year of study†

 Yr 1 and 2 24.8 (23.5–26.1)

 Yr 1 29.2 (27.2–31.2)

 Yr 2 20.6 (19.1–22.3)

Study site

 Chicago 26.7 (25.0–28.4)

 Nashville 21.9 (20.0–23.8)

Age group

 18–49 yr 6.7 (6.1–7.3)

 50–64 yr 26.3 (24.1–28.7)

 65–79 yr 63.0 (56.4–70.3)

 ≥80 yr 164.3 (141.9–189.3)

Pathogen detected‡

 Human rhinovirus 2.0 (1.7–2.3)

 Influenza A or B virus 1.5 (1.3–1.8)

  Streptococcus pneumoniae 1.2 (1.0–1.4)

 Human metapneumovirus 0.9 (0.7–1.2)

 Parainfluenza virus 0.8 (0.6–1.0)

 Respiratory syncytial virus 0.7 (0.5–0.9)

 Coronavirus 0.6 (0.4–0.7)

  Mycoplasma pneumoniae 0.5 (0.4–0.7)

  Staphylococcus aureus 0.4 (0.3–0.6)

  Legionella pneumophila 0.4 (0.2–0.5)

 Adenovirus 0.4 (0.2–0.5)
*

Analyses were based on 10,511,911 person-years of observation.

†

Annual incidence rates were calculated from July 1, 2010, to June 30, 2011, for year 1 and from July 1, 2011, to June 30, 2012, for year 2 and represent the 2061 of 2320 adults (89%) who had radiographic evidence of pneumonia and were enrolled during that time.

‡

Pathogen-specific incidence was calculated for the 2004 adults who had radio-graphic evidence of pneumonia during the incidence period and who had at least one specimen available for both bacterial and viral testing. Pathogen-specific incidence was only calculated for pathogens that were detected in more than 1% of adults.