FIG. 3.
Gingival gene expression in P. gingivalis-infected BALB/cByJ and A/J mice relative to the expression in sham-infected mice 1 week postinfection (GPR, >0.4). Genes are arranged in order of their GPR scores. The ΔCt for the genes in each mouse were then calculated by comparison with the value for 18S rRNA, and the ΔCt data for sham-infected mice were compared with the data for infected mice with a t test to derive the P value. The fold changes indicate the differences in the mean ΔCt values between the sham-infected mice and the infected mice. Each group contained three mice, and one QPCR was performed per mouse. In BALB/cByJ mice, expression of Il1b, Opg, and Stat6 was significantly increased in infected mice. In A/J mice, gene expression did not change significantly with infection. N.S., not significant.