FIG. 2.
Genes with significantly different basal expression levels in the BALB/cByJ and A/J strains of mice (GPR, >0.4). Genes are arranged in order of their GPR scores. The ΔCt for the genes in each mouse was calculated compared with the value for 18S rRNA, and the ΔCt data grouped by mouse strain was subjected to a t test to derive the P value. The fold changes quantify the differences in the mean ΔCt values between the two mouse strains. Each group contained four to eight mice, and one QPCR was performed per tissue from each mouse. (A) In the gingiva, Il1b, Opg, and Tnf mRNA were more highly expressed in the BALB/cByJ mice than in the A/J mice, while expression of Il15 was higher in A/J mice. (B) In the spleen, Il1b expression was 68-fold higher in BALB/cByJ mice than in A/J mice, while Selp expression was 5.6-fold higher in A/J mice than in BALB/cByJ mice.