Figure 3. Diagnostic imaging modalities used in murine models of cancer.
A) Representative PET and CT images using C11-methionine for a Ewing sarcoma orthotopic xenograft in the femur. B) Photograph of an immunocompromised mouse with an orthotopic rhabdomyosarcoma xenograft that is labeled with firefly luciferase for Xenogen imaging. C) MRI image of an orthotopic neuroblastoma xenograft (red) in the para-adrenal space adjacent to the kidney (green). D) 3D ultrasound of the same neuroblastoma xenograft shown in (C). E) X-ray image of an orthotopic Ewing sarcoma tumor showing the “hair-on-end” appearance that is typical of Ewing sarcoma.
