Table S2.
Common hallmark E2F targets leading-edge genes found within all three gene signatures
| Gene symbol | Gene name |
| PTTG1 | Pituitary tumor-transforming 1 |
| ANP32E | Acidic (leucine-rich) nuclear phosphoprotein 32 family member E |
| GINS1 | GINS complex subunit 1 |
| UBE2T | Ubiquitin-conjugating enzyme E2T |
| CDCA3 | Cell division cycle associated 3 |
| TCF19 | TCF19 |
| BARD19 | BRCA1-associated RING domain 1 |
| CIT | Citron (rho-interacting, serine/threonine kinase 21) |
| HELLS | Helicase, lymphoid specific |
| MCM6 | Minichromosome maintenance complex component 6 |
| TIPIN | TIMELESS interacting protein |
| MXD3 | MAX dimerization protein 3 |
| DIAPH3 | Diaphanous-related formin 3 |
| MCM4 | Minichromosome maintenance complex component 4 |
| POLD1 | Polymerase (DNA directed), delta 1, catalytic subunit |
| TRIP13 | Thyroid hormone receptor interactor 13 |
| TOP2A | Topoisomerase (DNA) II alpha 170 kDa |
| TMPO | Thymopoietin |
| PCNA | Proliferating cell nuclear antigen |
| DNMT | DNA (cytosine-5-)-methyltransferase 1 |
| PLK1 | Polo-like kinase 1 |
| POLA2 | Polymerase (DNA directed), alpha 2, accessory subunit |
| CHEK2 | Checkpoint kinase 2 |
| PRKDC | Protein kinase, DNA-activated, catalytic peptide |
| CKS1B | CDC28 protein kinase regulatory subunit 1B |
| SSRP1 | Structure specific recognition protein 1 |
| MCM3 | Minichromosome maintenance complex component 3 |
| DSCC1 | DNA replication and sister chromatid cohesion 1 |
| MCM2 | Minichromosome maintenance complex component 2 |
| GINS3 | GINS complex subunit 3 |
| NASP | Nuclear autoantigen sperm protein |
| DCLRE1B | DNA cross-link repair 1B |
| NUP107 | Nucleoporin 107 kDa |
| SUV39H1 | Suppressor of variegation 3–9 homolog 1 |