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. 2015 Nov 26;5:16778. doi: 10.1038/srep16778

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The average number of trials to criterion for PFC-PV-TeLC (blue) (A) and for PFC-Lesion (red) animals (B) was similar to respective controls (green and grey) during acquisition (left) but significantly different during reversal (right) learning. (C,D) During initial water maze training PFC-PV-TeLC (C; n = 17) and PFC-Lesion (D); n = 13) animals show small differences when compared to their respective controls (n = 15 and 9), but all animals acquire the task to the same standard. (E,F) After re-location of the platform both PFC-PV-TeLC (E) and PFC-Lesion (F) animals are significantly impaired at learning the new platform location. Data are mean ± s.e.m. *P < 0.05; ***p < 0.001.