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. 2015 Jun 1;5:10760. doi: 10.1038/srep10760

Figure 3. Model of the β-arrestin-1/ERK signaling module.

Figure 3

Color code: β-arrestin in grey, c-Src in blue, Raf1 in green, Mek1 in yellow, Erk1 in dark red; experimentally identified residues are in red, other potentially important residues are in orange, phosphorylation sites are in dark blue. A: c-Src/β-arrestin interaction, SH3 domain and its interacting peptide of PDB 1AD5 in violet. B: Raf1/β-arrestin interaction. C: Mek1/β-arrestin interaction. D: Erk1/β-arrestin interaction. E: Mek1/Erk1 interaction. F: Raf1/Mek1 interaction, the region 270-307 figured by a red dashed line is unfolded.