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. 2015 Nov 13;6:240. doi: 10.3389/fneur.2015.00240

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Copyright © 2015 Smith, Xiong, Elkind, Putnam and Cohen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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GFAP labeling following LFPI. (A) Example photomicrograph of contralateral hippocampus from LFPI animal. (B) Example photomicrograph of hippocampus ipsilateral to LFPI, inset displaying astrocyte morphology. (C) Example photomicrograph of ipsilateral hippocampus from sham-operated animal. (D) Example photomicrograph of contralateral mPFC from LFPI animal. (E) Example photomicrograph of mPFC ipsilateral to LFPI, inset displaying astrocyte morphology. (F) Example photomicrograph of ipsilateral mPFC from sham-operated animal. GFAP labeling in red, Hoescht labeling for DNA in blue. Scale bars: 200 μm in (A)–(F); 10 μm in insets. Asterisk (*) indicates region selected for inset. Yellow trapezoid in (E,F) outlines prelimbic cortex, where all physiology experiments were performed.