Fig. 2.
Different doses of tamoxifen affect bone. One-month-old male mice were treated with TAM at 0 (placebo), 1, 10, or 100 mg/kg/day × 4 days, or a single 100 mg or 300 mg dose. Distal femoral BV/TV (A, B), femur length (C), maximal load (D), and serum bone turnover markers (E and F) were measured at one month post-treatment. N = 6–8 mice per group; *, P < 0.05; **, P < 0.01.
