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. Author manuscript; available in PMC: 2015 Oct 28.
Published in final edited form as: Semin Reprod Med. 2009 Feb 5;27(1):52–61. doi: 10.1055/s-0028-1108010

Figure 1.

Figure 1

Pattern of epidermal growth factor (EGF)-like growth factor mRNA expression during follicle growth and ovulation. Microarray analysis was performed to evaluate the expression of EGF-like growth factor mRNAs in immature wild-type mouse ovaries primed with pregnant mare serum gonadotropin (PMSG) to promote follicle development to the preovulatory stage, and 48 hours later by human chorionic gonadotropin (hCG) to promote differentiation of follicular cells and ovulation. Ereg, Areg, and Btc mRNAs were rapidly and transiently increased in mouse ovaries in response to an ovulatory dose of hCG, whereas Tgf-α, Hb-Egf, and Egf mRNAs were not affected by this stimulus.