Fig. 5.
Liver morphology analysis from mice with MET+CAT initiated liver tumors treated with IL-18+IL-12. MET+CAT was hydrodynamically transfected and on days 22–24, 28–31 mice were treated with VC or IL-18+IL-12. (A) Livers were harvested on day 55 (B) and tissue sections were stained for β-catenin surrogate marker or (C) H&E. (D) Serum luciferase levels (left y-axis) and liver weight (right y-axis) was compared per mouse. (E) Linear regression analysis was performed on serum luciferase levels vs tumor weight dotted live represents 95% confidence band.
