Table 6.
Comparison of MN and HI titres of influenza B viruses (Yamagata-lineage)
| Viruses | Genetic clade-amino acid identities at HA1 positions 196-198 | Virus passage history** | Post-infection ferret antisera*; MN/HI titres | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| B/Florida/4/2006 | B/Wisconsin/1/2010 | B/Estonia/55669/2011 | B/Massachusetts/02/2012 | |||||||
| MN | HI | MN | HI | MN | HI | MN | HI | |||
| Reference virus | ||||||||||
| B/Florida/4/2006 | 1-DKT | E7 | 540 | 640 | 161 | 160 | 61 | 160 | 796 | 640 |
| B/Wisconsin/1/2010 | 3-DKT | E5 | 844 | 160 | 330 | 160 | 41 | 10 | 450 | 320 |
| B/Estonia/55669/2011 | 2-NKT | M2 | 71 | 160 | 24 | 80 | 152 | 640 | 155 | 160 |
| B/Massachusetts/02/2012 | 2-DKT | E7 | 663 | 320 | 133 | 160 | ND*** | 80 | 734 | 640 |
| Test virus | ||||||||||
| B/Denmark/8/2012 | 3-NKT | M3 | 170 | 80 | 52 | 10 | 159 | 80 | 231 | 160 |
| B/Denmark/3/2012 | 3-NKT | M4 | 239 | 40 | 134 | 40 | 73 | 20 | 99 | 80 |
| B/Ireland/13M98449/2013 | 3-NKT | Cx | 187 | 40 | 129 | 40 | 32 | 40 | 112 | 80 |
| B/Hong Kong/432/2013 | 3-NKT | M2 | 203 | 80 | 140 | 40 | 25 | 40 | 130 | 160 |
| B/Stockholm/8/2012 | 2-NKT | M2 | 226 | 80 | 136 | 80 | 95 | 640 | 95 | 80 |
| B/Paris/2327/2013 | 2-NKT | M2 | 213 | 40 | 77 | 40 | 94 | 160 | 106 | 80 |
| B/Cameroon/13v-2053/2013 | 2-NKT | M2 | 120 | 40 | 51 | 20 | 63 | 320 | 100 | 80 |
| B/Moldova/462/2013 | 2-NKT | M2 | 143 | 40 | 48 | 20 | 149 | 640 | 91 | 80 |
Raised against the viruses indicated; homologous titres for reference viruses are shown in boldface type.
Passage in eggs (E); MDCK cells (M); cells of unspecified type (C); numbers indicate the number of passages (x = unknown number).
Not done.