Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Action potential properties of CA1 pyramidal neurons in hippocampal slices from 20 to 23 month old PDAPP mice and age-matched WT littermate controls.
| WT n = 27 | PDAPP n = 30 | ||||
|---|---|---|---|---|---|
| Property | Average | SEM | Average | SEM | p |
| AP_peak (mV) | 25.05 | 1.53 | 20.24 | 1.71 | 0.04 |
| AP_width (ms) | 0.83 | 0.03 | 0.74 | 0.03 | 0.04 |
| AP_thres (mV) | −58.64 | 0.81 | −58.46 | 0.90 | 0.88 |
| AP_max_dvdt (Vs−1) | 371.43 | 17.43 | 335.21 | 15.73 | 0.13 |
| AP_AHP (mV) | 2.46 | 0.28 | 4.62 | 0.80 | 0.02 |
