. 2015 Oct 1;5(8):505–516. doi: 10.1089/brain.2014.0327

Table 2.

Mediation Models

C	N_x−C	N_x−N_m	N_m−C	N_x−N_m−C	N_x′−C
N_x=DN, N_m=FPCN
Speed	0.19^a	0.70^a	0.17^a	0.12^a	0.07
Executive function	0.15^a	0.70^a	0.29^a	0.20^a	−0.05
Memory	0.16^a	0.70^a	0.16	0.11	0.05
Global	0.19^a	0.70^a	0.23^a	0.16^a	0.03
N_x=SN, N_m=FPCN
Speed	0.14^a	0.62^a	0.22^a	0.13^a	0.01
Executive function	0.10	0.62^a	0.31^a	0.19^a	−0.09
Memory	0.14^a	0.62^a	0.17^a	0.10^a	0.04
Global	0.15^a	0.62^a	0.26^a	0.16^a	−0.01

Standardized path coefficients for mediation models involving FPCN as a mediator of the network to cognition relationships for the DN and SN. Refer to Figure 5 (left) for model structure. Network measures were controlled for age and quality assessment metrics before entry in the models. N_x−N_m−C indicates the indirect (mediated) effect of N_x on C through N_m. N_x′−C indicates the direct effect of N_x on C after controlling for the indirect effect of N_m.

^{^a}

Path value is significant with 95% confidence intervals not overlapping 0.